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No specific dose adjustment advised when tofacitinib coadministered with potent CYP2C19 inhibitors; minimize tofacitinib dose if coadministered with each average CYP3A4 and strong CYP2C19 inhibitors .Ferraro et al (1997b) examined the in vivo dopamine and GABA amounts of the nucleus accumbens in rats offered modafinil, they usually discovered that